SNU Big Data Knowledge Information Platform
Full Menu
AI
Your Browsing History
10 More
loading...
Report registration
Paper List
Metformin attenuates an increase of calcium-dependent and ubiquitinproteasome markers in unloaded muscle
Author
Belova S.P.,Zaripova K.,Sharlo K.,Kostrominova T.Y.,Shenkman B.S.,Nemirovskaya T.L.
Journal Title
Journal of Applied Physiology
Publication Year
2022
Topics
Summary
This study tested the hypothesis that metformin can regulate calcium-dependent signaling pathways, markers of protein synthesis, and the expression of E3 ubiquitin ligases during skeletal muscle unloading. Metformin inhibited unloading-induced changes in muscle, preventing the decrease of p-AMPK and increase of ATP content, and attenuating the increase in key markers of calcium-dependent and ubiquitin-proteasome pathways.
Related Content
LikeSNU analyzes your query semantically to recommend related resources.
-
The Plasticity of Skeletal Muscle : From Molecular Mechanism to Clinical Applications
-
Regulation of smooth muscle contraction
-
The functions, disease-related dysfunctions, and therapeutic targeting of neuronal mitochondria
-
Cardiac cell biology
-
Nutrients and cell signaling
-
Signalling from internalized growth factor receptors
-
Excitation-contraction coupling in skeletal, cardiac, and smooth muscle
-
Proteases II : potential role in health and disease
-
Taurine 8
-
Role of melatonin and pineal peptides in neuroimmunomodulation
-
Signal transduction and protein phosphorylation
-
Taurine in health and disease
-
Enkephalins and endorphins : stress and the immune system
-
The unfolded protein response and cellular stress.
-
Uterine function : molecular and cellular aspects
-
Current Topics in Developmental Biology.
-
Protein-protein interactions in plant biology
-
Matrix proteases in health and disease
-
Current topics in developmental biology.
-
The unfolded protein response and cellular stress.
Previous
Next
Previous
Next
Previous
Next