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Effects of Gintonin-enriched fraction on the gene expression of six lysophosphatidic receptor subtypes
Author
Lee R.,Lee B.H.,Choi S.H.,Cho Y.J.,Cho H.S.,Kim H.C.,Rhim H.,Cho I.H.,Rhee M.H.,Nah S.Y.
Journal Title
Journal of Ginseng Research
Publication Year
2021
Topics
Summary
This study investigated the effects of gintonin, a lysophosphatidic acid (LPA) receptor ligand extracted from ginseng, on the gene expression of six LPA receptor subtypes (LPARS) in a tissue-specific manner. Long-term oral administration of GEF (Gintonin-enriched fraction) to mice for 21 days revealed differential regulation of LPA6 receptor expression, increasing in the liver, small intestine, colon, and testis, while decreasing in the brain, heart, lungs, and kidneys.
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