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논문 목록
Water-responsive shape memory thermoplastic polyurethane scaffolds triggered at body temperature for bone defect repair
저자
Shuai C.,Wang Z.,Peng S.,Shuai Y.,Chen Y.,Zeng D.,Feng P.
학술지명
Materials Chemistry Frontiers
출판/발행연도
2022
주제
요약
본 연구에서는 체온에서 작동하는 물 반응성 형상 기억 특성을 가진 생체 적합성 열가소성 폴리우레탄(TPU) 골 스캐폴드를 선택적 레이저 소결(SLS)을 통해 제작하였다. 물 분자는 TPU 내 수소 결합을 끊고 재결합하여 형상 고정 및 회복을 유도하며, 24시간 침지 시 형상 고정률 67%, 형상 회복률 90%를 달성하였다. 제작된 스캐폴드는 세포 부착 및 방향성 세포 증식을 촉진하여 골 결손 복구에 유망한 후보 물질임을 입증하였다.
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