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논문 목록
α-tocopheryl succinate inhibits osteolytic bone metastasis of breast cancer by suppressing migration of cancer cells and receptor activator of nuclear factor-κΒ ligand expression of osteoblasts
저자
Kim, Bongjun ; Kim, Hong Hee; Lee, Zang Hee
학술지명
대한골대사학회지
출판/발행연도
2018
주제
요약
α-토코페릴 숙시네이트(αTP-suc)는 유방암 세포의 이동을 억제하고 파골세포 활성화에 관여하는 RANKL 발현을 억제하여 골 용해성 골 전이를 억제하는 효과를 보였다. 생체 내 실험 결과, αTP-suc는 골 전이 감소, 골파괴 완화, 종양 부담 및 파골세포 수 감소를 유도하는 것으로 나타났다.
학술지 영향력
[대한골대사학회지]
- CiteScore
- 3.2
- KCI
- 0.26
- SJR
- 0.611
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