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GDF15 Contributes to Radioresistance by Mediating the EMT and Stemness of Breast Cancer Cells
저자
Zhao X.,Liu X.,Hu S.,Pan Y.,Zhang J.,Tai G.,Shao C.
학술지명
International Journal of Molecular Sciences
출판/발행연도
2022
주제
요약
본 연구는 유방암 방사선 저항성과 관련된 GDF15 유전자를 발굴하고, GDF15 발현 증가는 상피-중간엽 전이 및 줄기세포 특성 증가와 관련이 있음을 확인했습니다. GDF15 유전자 발현을 억제하면 방사선 저항성을 감소시키고 상피-중간엽 전이 및 줄기세포 특성을 억제하여, GDF15가 유방암 방사선 저항성에 기여함을 밝혔습니다.
학술지 영향력
[International Journal of Molecular Sciences]
- CiteScore
- 9.0
- ES
- 0.43083
- JCI
- 0.71
- JCR
- 4.9
- SJR
- 1.273
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