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논문 목록
Encapsulation of polyphenols in pH-responsive micelles self-assembled from octenyl-succinylated curdlan oligosaccharide and its effect on the gut microbiota
저자
Li H.,Gao Z.,Xu J.,Sun W.,Wu J.,Zhu L.,Gao M.,Zhan X.
학술지명
Colloids and Surfaces B: Biointerfaces
출판/발행연도
2022
주제
요약
옥테닐 숙신산 무수물 변성 커들란 올리고당(MCOS) 기반의 양친매성 고분자를 합성하여 pH 감응성 미셀을 형성하고, 폴리페놀(커큐민, 퀘르세틴)을 봉입하여 장내 미생물에 미치는 영향을 연구했습니다. MCOS 미셀은 pH 의존적 방출 특성을 보였으며, 장내 미생물에 의해 단쇄 지방산 생성을 촉진하고 비피도박테륨 증식을 증가시키며 대장균_시겔라 성장을 억제했습니다.
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