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논문 목록
A branched-chain amino acid-based metabolic score can predict liver fat in children and adolescents with severe obesity
저자
Lischka J.,Schanzer A.,Hojreh A.,Ba Ssalamah A.,Item C.B.,de Gier C.,Walleczek N.K.,Metz T.F.,Jakober I.,Greber-Platzer S.,Zeyda M.
학술지명
Pediatric Obesity
출판/발행연도
2021
주제
요약
본 연구는 심각한 비만을 겪는 소아 및 청소년에서 NAFLD 예측을 위한 새로운 바이오마커를 조사하고, 비분지쇄 아미노산(BCAA) 기반 대사 점수가 간지방을 예측할 수 있음을 확인했습니다. BCAA, ALT, GGT, 페리틴, 인슐린을 포함하는 선형 회귀 모델은 MRI-PDFF를 예측했으며, 기존 점수보다 우수한 성능을 보였습니다.
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