LikeSNU-서울대 중앙도서관 빅데이터 지식 플랫폼

Au nanozyme-driven antioxidation for preventing frailty

Author

Kim J.,Oh S.,Shin Y.C.,Wang C.,Kang M.S.,Lee J.H.,Yun W.,Cho J.A.,Hwang D.Y.,Han D.W.,Lee J.

Journal Title

Colloids and Surfaces B: Biointerfaces

Publication Year

2020

Topics

Summary

This study developed a nanozyme (GI-Au NZs) composed of gold nanoparticles and phytochemicals (gallic acid, isoflavone) to address oxidative stress associated with aging and frailty, and evaluated its effects. Cell and in vivo experiments demonstrated that the nanozyme inhibited senescence in fibroblasts and reduced oxidative stress in mouse skin, with no observed hepatotoxicity or nephrotoxicity.

Journal Influence

[Colloids and Surfaces B: Biointerfaces]