서울대학교 빅데이터 지식정보플랫폼
전체 메뉴
AI 검색
최근 확인한 콘텐츠
8건 더보기
loading...
반출리포트 생성
논문 목록
Loratadine, an antihistamine drug, exhibits anti-inflammatory activity through suppression of the NF-kB pathway
저자
Hunto S.T.,Kim H.G.,Baek K.S.,Jeong D.,Kim E.,Kim J.H.,Cho J.Y.
학술지명
Biochemical Pharmacology
출판/발행연도
2020
주제
요약
로라타딘은 NF-kB 경로를 억제하여 항염증 활성을 나타내는 항히스타민제이며, RAW264.7 세포 및 마우스 모델에서 염증 반응을 억제하는 효과를 보였다. 특히 Syk 및 Src 단백질에 결합하여 NF-kB 신호 전달 경로를 억제하는 기전을 밝혀냈다.
연관 콘텐츠
LikeSNU에서 의미기반으로 분석하여 연관된 자료를 추천해드립니다.
-
Prostanoids and drugs
-
Immunoreceptor tyrosine-based inhibition motifs
-
Histamine and H1-receptor antagonists in allergic disease
-
Deoxynucleoside analogs in cancer therapy
-
Prostaglandins, leukotrienes, and the immune response
-
Bioactive natural products : chemistry and biology
-
Trends in neuroimmunology
-
Role of melatonin and pineal peptides in neuroimmunomodulation
-
Small peptides : chemistry, biology, and clinical studies
-
Lysosomes : biology, diseases, and therapeutics
-
Struktur und Absorptionsspektros-kopie organischer Naturstoffe
-
Immunopharmaceuticals
-
Targeting protein kinases for cancer therapy
-
Classics in Total Synthesis IV : New Targets, Strategies, Methods
-
![NF-[kappa]BRel transcription factor family](https://image.aladin.co.kr/product/503/29/cover/0387335722_1.jpg)
NF-[kappa]BRel transcription factor family
-
Plant amino acids : biochemistry and biotechnology
-
Glucocorticoid receptor-based transrepressive mechanisms : at promoters of inflammatory genes
-
Drug resistance in leukemia and lymphoma III
-
COX-2 blockade in cancer prevention and therapy
-
Nutrients and cell signaling
이전
다음
이전
다음
이전
다음