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A Novel Stable Crystalline Triamcinolone Acetonide-loaded PLGA Microsphere for Prolonged Release After Intra-Articular Injection

Author
Myoung Jin Ho, 김성래, 최영욱, 강명주
Journal Title
Bulletin of the Korean Chemical Society
Publication Year
2016
Summary

This study aimed to fabricate novel poly(lactic-co-glycolic acid) microspheres (PLGA MSs) containing triamcinolone acetonide (TA) for sustained drug release after intra-articular injection. The fabricated MSs achieved 80% drug release after 48 hours with stable crystalline form and maintained stability for 6 months under long-term storage conditions.

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