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Anti-Inflammatory Activity of Ethanolic Extract from Skipjack Tuna (Katsuwonus pelamis) Heart in LPS-Induced RAW 264.7 Cells and Mouse Ear Edema Model
저자
Bo
학술지명
Food Science and Biotechnology
출판/발행연도
2016
주제
요약
본 연구는 참다랑어 심장에서 추출한 에탄올 추출물(THEE)의 항염증 효과를 LPS로 유도된 RAW 264.7 세포와 마우스 귀 부종 모델에서 확인했습니다. THEE는 염화질소(NO), 인터류킨-6(IL-6), 종양 괴사 인자-α(TNF-α) 및 IL-1β의 생성을 용량 의존적으로 억제했으며, NF-κB 및 MAPK 활성 억제를 통해 항염증 효과를 나타냈습니다.
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