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Inhibitory Effects of Syzygium aromaticum Ethanol Extracts on IgE Mediated RBL-2H3 cell Activation
저자
정준희, 김용민, 박종필, 김태연, 김이화
학술지명
Korean Journal of Acupuncture
출판/발행연도
2014
주제
요약
본 연구는 정향 에탄올 추출물(SAE)이 RBL-2H3 세포 매개 알레르기 반응에 미치는 영향과 작용 기전을 조사했습니다. SAE는 세포 독성을 나타내지 않았으며, IgE에 의해 유도된 p38 MAPK 활성화를 차단하여 RBL-2H3 세포의 탈과립 및 히스타민 분비를 용량 의존적으로 억제했습니다.
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