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Polyurethane membrane with porous surface for controlled drug release in drug eluting stent
저자
서은하, 나건
학술지명
생체재료학회지
출판/발행연도
2014
주제
요약
본 연구는 암 성장 억제 및 약물 방출 조절을 위해 다공성 표면을 가진 폴리우레탄 막을 이용한 약물 용출 스텐트를 개발했습니다. 폴리에틸렌 글리콜을 폴리우레탄 막에 통합하여 파클리탁셀과 같은 소수성 항암제의 방출을 제어하고, 파클리탁셀의 결정화를 억제하여 약물 방출 기간을 연장했습니다.
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