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Quantitative and Qualitative Analysis of Alkaloids in Coptis chinensis (Coptidis Rhizoma) by LC-DAD and LC-ESI/MS
저자
유영법, 배창휴
학술지명
한국자원식물학회지
출판/발행연도
2017
주제
요약
본 연구는 기능성 식품, 의약품, 화장품 산업에서 품질 관리를 위해 Coptis chinensis (Coptidis Rhizoma)의 마커 물질인 베르베린의 정량 분석을 HPLC-DAD를 통해 검토했습니다. 개발된 HPLC 방법은 FDA 및 ICH 권장 사항을 충족했으며, 베르베린 함량은 4.25%로 계산되었고, HPLC-ESI/MS 방법을 통해 베르베라스틴, 팔마틴, 콜럼바민 등 다양한 알칼로이드를 확인했습니다.
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