서울대학교 빅데이터 지식정보플랫폼
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LPS로 유도된 RAW264.7 대식세포에 대한헛개나무(Hovenia dulcis) 추출물의 항염증 효과
저자
우현심, 이선민, 허정두, 이민성, 김영수, 김대욱
학술지명
한국자원식물학회지
출판/발행연도
2018
주제
요약
본 연구는 헛개나무 잎, 줄기, 뿌리 추출물의 항염증 효과를 RAW264.7 세포에서 확인한 결과, 뿌리 추출물이 가장 강력한 효과를 나타냈다. 뿌리 추출물은 NF-kB 및 MAPK 신호전달 경로를 억제하고 Nrf2를 활성화시켜 염증 반응을 감소시켰으며, 주요 성분인 27-O-protocatechuoylbetulinic acid 또한 항염증 효과를 보였다.
학술지 영향력
[한국자원식물학회지]
- KCI
- 0.75
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![Plant hormone signal perception and transduction: proceedings of the International Symposium on Plant Hormone Signal Perception and Transduction, Moscow, Russia, September 4-10, 1994:: edited by A.R. Smith ... [et al.].](https://image.aladin.co.kr/product/524/57/cover/0792337689_2.jpg)
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