LikeSNU-서울대 중앙도서관 빅데이터 지식 플랫폼

Estimation of p-values with Two Dimensional Null Distributions from Genomic Data Set

Author

이재용, 박미라

Journal Title

Journal of The Korean Data Analysis Society

Publication Year

2018

Topics

#Null distribution
#Statistics
#Mathematics

Summary

This study proposes a method for estimating p-values using two-dimensional null distributions in genomic data. While genome-wide association studies typically focus on single phenotypes, investigating genotypes associated with multiple phenotypes requires multidimensional null distributions. The proposed method utilizes a positioning parameter inspired by the extension of the Kolmogorov-Smirnov statistic to compare the positions of points in two-dimensional data.

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