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갈근탕 혼합단미엑스제 및 전탕액의 성분 및 생리활성 비교 연구

Author
김정옥, 김세진, 김종범, 남원희, 이지범, 이화동
Journal Title
동의생리병리학회지
Publication Year
2019
Topics
Summary

This study compared the ingredient and efficacy of Galgeun-tang (GGT) mix extract powder and decoction using HPLC analysis to determine the content of ten index components, antioxidant effect, and anti-inflammatory effect. The GGT mix extract powder contained higher puerarin and daidzin content, while the GGT decoction contained higher cinnamic acid and glycyrrhizic acid content, but the overall composition was similar. The GGT decoction also showed a slightly higher antioxidant effect, and both formulations similarly inhibited the production of NO, iNOS, COX-2, TNF-α, IL-1β, and IL-6 in LPS-induced RAW 264.7 macrophages.

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