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논문 목록
Astragalin reduces lipopolysaccharide-induced acute lung injury in rats via induction of heme oxygenase-1
저자
Donghua Zheng, Dawei Liu, Na Liu, Yukun Kuang, Qiang Tai
학술지명
Archives of Pharmacal Research
출판/발행연도
2019
주제
요약
아스트라갈린은 지질다당류(LPS) 유발 급성 폐 손상(ALI)에서 헤모옥시게나제-1(HO-1) 발현을 유도하여 항염증 및 항산화 효과를 나타냅니다. 연구 결과, 아스트라갈린은 폐 염증 세포 침윤 및 폐부종을 억제하고, HO-1 활성을 증가시켜 산화 스트레스 지표를 감소시켰으며, HO-1 억제 시 이러한 보호 효과는 사라졌습니다.
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