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Dendropanax morbifera Branch Water Extract Increases the Immunostimulatory Activity of RAW264.7 Macrophages and Primary Mouse Splenocytes

Author
송지혜, 곽성민, 김현희, 전우진, 이정민, 윤호근, 김용재, 최경철
Journal Title
Journal of Medicinal Food
Publication Year
2019
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Summary

Dendropanax morbifera branch water extract (DBW) enhanced immunostimulatory activity by increasing the expression of cytokines and immune effector molecules in RAW264.7 macrophages and splenocytes. DBW treatment promoted NF-κB signaling activation, leading to increased expression of proinflammatory cytokines and effector molecules, and in vivo experiments showed increased splenocyte cytokines, nitric oxide production, and natural killer cell activity.

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