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Hepatoprotective effect of sodium hydrosulfide on hepatic encephalopathy in rats

Author
권경완, 남윤진, 최원석, 김태욱, 김건민, 손의동
Journal Title
The Korean Journal of Physiology & Pharmacology
Publication Year
2019
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Summary

This study investigated the hepatoprotective effect of hydrogen sulfide in rats with hepatic encephalopathy. Administration of sodium hydrosulfide (NaHS) reduced levels of aspartate aminotransferase and alanine aminotransferase, indicators of liver disease, and significantly decreased ammonia levels, a major causative factor of hepatic encephalopathy. These results suggest that NaHS exhibits hepatoprotective effects and protects against neurotoxicity through antioxidant and anti-inflammatory actions.

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