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논문 목록
A positive feedback loop between ZNF205-AS1 and EGR4 promotes non-small cell lung cancer growth
저자
He S.,Lin J.,Xu Y.,Lin L.,Feng J.
학술지명
Journal of Cellular and Molecular Medicine
출판/발행연도
2019
주제
요약
본 연구는 비소세포폐암(NSCLC)과 관련된 새로운 lncRNA인 ZNF205-AS1을 발굴하고, ZNF205-AS1과 EGR4가 양성 피드백 루프를 형성하여 NSCLC 성장을 촉진한다는 것을 밝혀냈다. ZNF205-AS1은 EGR4의 발현을 증가시키고, EGR4는 ZNF205-AS1의 발현을 증가시키는 상호작용을 통해 NSCLC 세포 및 종양 성장을 촉진하는 것으로 나타났다.
학술지 영향력
[Journal of Cellular and Molecular Medicine]
- CiteScore
- 8.7
- ES
- 0.03296
- JCI
- 0.86
- JCR
- 4.2
- SJR
- 1.264
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