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BLU-5937: A selective P2X3 antagonist with potent anti-tussive effect and no taste alteration
저자
Garceau D.,Chauret N.
학술지명
Pulmonary Pharmacology and Therapeutics
출판/발행연도
2019
주제
요약
BLU-5937은 강력하고 선택적인 P2X3 수용체 길항제로, 만성 기침의 원인이 되는 기침 반사 과민성을 억제하여 항기침 효과를 나타냅니다. 동물 모델에서 histamine 및 ATP에 의해 유도된 기침을 현저히 감소시키며, 맛 감각에는 영향을 미치지 않습니다.
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