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Smallanthus sonchifolius leaf attenuates neuroinflammation

Author
백수지, 최난희, 이강파, 전현정, 김지수
Journal Title
Physical Activity and Nutrition
Publication Year
2018
Summary

This study investigated the neuroprotective effects of yacon leaf extract (YLE) against lipopolysaccharide (LPS)-induced neuroinflammation in both in vitro and in vivo models. YLE significantly reduced nitric oxide production in microglia and decreased mRNA levels of inflammatory factors. Furthermore, YLE alleviated LPS-induced brain damage, suggesting its potential for preventing neurodegenerative diseases.

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