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Inhibition of Cell Growth by Anoikis in Various Human Cancer Cell Lines Treated with an Extract of Smilax china L.
저자
김민재, 김현지, 김무경, 이성호, 전병균
학술지명
생명과학회지
출판/발행연도
2021
주제
요약
본 연구는 Smilax china L. 추출물(SCLE)이 다양한 인간 암세포주(A-549, MCF-7, MDA-MB-231, U87-MG, AGS, MKN-74, SNU-601)에서 세포 독성을 나타냄을 확인했습니다. SCLE 처치 시 암세포의 성장이 억제되었고, 아노이키스와 유사한 부유 세포 형태가 관찰되었으며, 이는 Rho 의존성 기전과는 독립적으로 조절되는 것으로 보입니다.
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