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천궁으로부터 lipid의 분리 동정

Author
김형근, 전형주, 응우옌 트롱 응우옌, 이대영, 백남인
Journal Title
Journal of Applied Biological Chemistry
Publication Year
2021
Summary

Five lipids (methyl linoleate, linoleic acid, 6-linoleoyl-α-D-glucopyranosyl β-D-fructofuranoside, 1-linolenoyl-3-(α-D-galactopyranosyl (1→6)-β-D-galactopyranosyl) glycerol, and 1-linoleoyl-3-(α-D-galactopyranosyl (1→6)-β-D-galactopyranosyl) glycerol) were isolated and identified from the rhizomes of Cnidium officinalis. Compounds 1 and 3-5 were isolated from this plant for the first time, and compounds 3, 4, and 5 are rarely found in nature. These lipid compounds exhibit immune enhancement and anticancer activity, suggesting the potential of Cnidium officinalis rhizome as a source of pharmacologically active materials.

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