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논문 목록
Jageum-Jung, the herbal pharmaceuticals, inhibits the hepatic fibrogenesis as mediated with TGF-β1/smad signaling
저자
송유림, Jang Mi Hee, Jang Boyun, Bae Su Jin, Bak Seon Been, Lee Sung Min, Yun Un
학술지명
Molecular & Cellular Toxicology
출판/발행연도
2022
주제
요약
자음정(JGJ)은 간 섬유화에 관여하는 TGF-β1/smad 신호 전달을 억제하고, CCl4로 유도된 간 섬유화 마우스 모델에서 간 보호 효과를 나타냈다. JGJ 전처치는 TGF-β에 의해 유도된 섬유화 매개체 및 염증성 사이토카인의 발현을 감소시켰다.
학술지 영향력
[Molecular & Cellular Toxicology]
- CiteScore
- 2.7
- ES
- 0.00055
- JCI
- 0.29
- JCR
- 1.4
- KCI
- 0.16
- SJR
- 0.389
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