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Involvement of IKK/IkBα/NF-kB p65 Signaling into the Regulative Effect of Engeletin on MUC5AC Mucin Gene Expression in Human Airway Epithelial Cells
저자
Hossain Rajib, Kim Kyung
학술지명
Biomolecules & Therapeutics
출판/발행연도
2022
주제
요약
본 연구는 엔젤레틴이 인간 폐 상피 세포에서 MUC5AC 뮤신 유전자 발현에 미치는 영향을 조사했습니다. 엔젤레틴은 PMA에 의해 유도된 IkBα 분해 억제 및 NF-kB p65 핵 이동 억제를 통해 MUC5AC 뮤신 mRNA 발현 및 생성을 억제했습니다.
학술지 영향력
[Biomolecules & Therapeutics]
- CiteScore
- 6.2
- ES
- 0.00199
- JCI
- 0.73
- JCR
- 3.2
- KCI
- 0.36
- SJR
- 1.054
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