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Discovery of petroleum ether extract of eclipta targeting p53/Fas pathway for the treatment of chemotherapy-induced alopecia: Network pharmacology and experimental validation
저자
Wang W.,Wang H.,Luo Y.,Li Z.,Li J.
학술지명
Journal of Ethnopharmacology
출판/발행연도
2024
주제
요약
본 연구는 전통적인 한약재인 에클립타의 석유 에테르 추출물(PEE)이 네트워크 약리학 및 실험적 검증을 통해 항암 화학 요법으로 유발된 탈모에 미치는 영향을 조사했습니다. PEE는 p53/Fas 경로 억제를 통해 모낭 손상을 완화하고 모발 성장을 촉진하며, 세포 생존을 증가시키고 세포 사멸을 감소시키는 것으로 나타났습니다.
학술지 영향력
[Journal of Ethnopharmacology]
- CiteScore
- 10.4
- ES
- 0.02382
- JCI
- 1.44
- JCR
- 5.4
- SJR
- 1.142
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