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Renal Protective Effects of Sparstolonin B in a Mouse Model of Sepsis
저자
Chaeyeong Kim; Soo Ho Ryu; Nayeon Kim; Wonhwa Lee; Jong-Sup Bae
학술지명
Biotechnology and Bioprocess Engineering
출판/발행연도
2022
주제
요약
본 연구는 스파르스톨로닌 B(SsnB)가 패혈증 유발 마우스 모델에서 신장 기능 손상을 감소시킬 수 있는지 조사했습니다. 연구 결과, SsnB 처치는 혈뇨소질소 및 크레아티닌 수치를 증가시키고, 염증 반응을 억제하며, 항산화 시스템을 회복시켜 패혈증으로 인한 신장 손상으로부터 마우스를 보호하는 효과를 나타냈습니다.
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