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Risk calculators for the detection of prostate cancer: a systematic review

Author
Denijs, Frederique B.; van Harten, Meike J.; Meenderink, Jonas J. L.; Leenen, Renée C. A.; Remmers, Sebastiaan; Venderbos, Lionne D. F.; van den Bergh, Roderick C. N.; Beyer, Katharina; Roobol, Monique J.
Journal Title
Prostate Cancer and Prostatic Diseases
Publication Year
2024
Summary

This systematic review analyzed the current status of clinical risk calculators applicable to a prostate cancer early detection algorithm. A total of 96 unique risk calculators were identified, of which 45 underwent external validation and 28 were validated in multiple cohorts. While risk calculators contribute to mitigating the limitations of early detection, the lack of external validation data is a concern and should be considered when evaluating the applicability of a specific risk calculator.

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