SNU Big Data Knowledge Information Platform
Full Menu
AI
Your Browsing History
1 More
loading...
Report registration
Paper List
Multiple Myeloma Cell Drug Responses Differ in Thermoplastic vs PDMS Microfluidic Devices
Author
Moore, Thomas A.; Brodersen, Peter; Young, Edmond W. K.
Journal Title
Analytical Chemistry
Publication Year
2024
Topics
Summary
This study investigated the impact of microfluidic device material on drug responses in multiple myeloma cells, finding that PDMS devices exhibit higher drug absorption compared to thermoplastic devices, leading to bias in cytotoxicity measurements. ToF-SIMS analysis revealed significantly deeper drug absorption in PDMS, correlating with altered IC50 values. These results highlight the importance of material selection in microfluidic device design for accurate drug cytotoxicity assessments.
Journal Influence
[Analytical Chemistry]
- CiteScore
- 11.6
- ES
- 0.10393
- JCI
- 1.73
- JCR
- 6.7
- SJR
- 1.533
Related Content
LikeSNU analyzes your query semantically to recommend related resources.
-
Lab-on-a-chip : miniaturized systems for (bio)chemical analysis and synthesis
-
LC-MS in drug bioanalysis
-
Micro and nano flow systems for bioanalysis
-
Handbook of pharmaceutical controlled release technology
-
The ADME encyclopedia : a comprehensive guide on biopharmacy and pharmacokinetics
-
Polymers in medicine II : biomedical and pharmaceutical applications
-
Mass spectrometry in drug metabolism and pharmacokinetics
-
Mass spectrometry in drug metabolism ; proceedings
-
Polymers in medicine : biomedical and pharmaceutical applications
-
Polymeric drug delivery
-
Mass spectrometry in drug discovery
-
Polymeric drugs and drug delivery systems
-
ADME-enabling technologies in drug design and development
-
Cyclic-nucleotide phosphodiesterases in the central nervous system : from biology to drug discovery
-
Biomems and biomedical nanotechnology
-
Biomedical science and technology : recent developments in the pharmaceutical and medical sciences
-
Behavior of macromolecules
-
Microelectronics technology : polymers for advanced imaging and packaging : developed from a symposium sponsored by the ACS Division of Polymeric Materials: Science and Engineering, Inc., and the Polymers for Microelectronics Division of the Society of Polymer Science, Japan, at the 209th National Meeting of the American Chemical Society, Anaheim, California, April 2-6, 1995
-
Analysis of psychiatric drugs
-
Drug absorption enhancement : concepts,possibilities, limitations,and trends
Previous
Next
Previous
Next
Previous
Next