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논문 목록
Resveratrol upregulates miR-455-5p to antagonize cisplatin ototoxicity via modulating the PTEN-PI3K-AKT axis.
저자
Liu Y; Wu H; Zhang F; Yang J; He J
학술지명
Biochemistry and cell biology = Biochimie et biologie cellulaire
출판/발행연도
2021
주제
요약
본 연구는 레스베라트롤이 miR-455-5p 발현을 증가시켜 PTEN-PI3K-AKT 경로를 조절함으로써 시스플라틴으로 유발된 이독성을 억제하는 효과를 탐구합니다. 시험관 내 및 생체 내 실험 결과, 레스베라트롤은 세포 생존을 촉진하고 세포 사멸 및 산화 스트레스를 감소시키며, 청각 손실을 보호하는 효과를 나타냈습니다.
학술지 영향력
[Biochemistry and cell biology = Biochimie et biologie cellulaire]
- CiteScore
- 5.3
- ES
- 0.00188
- JCI
- 0.45
- JCR
- 2.3
- SJR
- 0.610
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